KMID : 0931320120120020055
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´ëÇÑ»óºÎÀ§Àå°ü.Ç︮ÄÚ¹ÚÅÍÇÐȸÁö 2012 Volume.12 No. 2 p.55 ~ p.61
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Epidemiology of Barrett¡¯s Esophagus
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Park Moo-In
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Abstract
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Barrett¡¯s esophagus was first described more than 50 years ago. Chronic gastroesophageal reflux disease can cause Barrett¡¯s esophagus, and predisposes the development of adenocarcinoma of the esophagus. Barrett¡¯s esophagus can be defined as the presence of specialized intestinal metaplasia within any length of the esophagus. However, there is still heterogeneity in definition of Barrett¡¯s esophagus, which has resulted in confusion and difficulties in comparing the various studies on the epidemiology of Barrett¡¯s esophagus. In Western countries, the incidence of Barrett¡¯s esophagus and esophageal adenocarcinoma has progressively increased. In contrast, the prevalence of Barrett¡¯s esophagus and esophageal adenocarcinoma is not increasing in Asia. Increased age, male sex, smoking, reflux symptoms and erosive esophagitis have been found to be risk factors for Barrett¡¯s esophagus in several studies from Asia. The prevalence of Barrett¡¯s esophagus in Asia outside Japan ranges from 0.06% to 6.2%, and is still lower than that in Western countries.
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KEYWORD
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Barrett¡¯s esophagus, Prevalence, Risk factors
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